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5 Key Reasons Why Distributors Should Invest in a Robust ERP

5 Key Reasons Why You Need ERP Software in Distribution

5 Key Reasons Why You Need ERP Software in Distribution 700 500 Xcelpros Team

At a Glance

  • As a distributor, your investments can be severely impacted due to operational or management issues with your transportation system; The day-to-day operations of most wholesale distribution companies can take advantage of optimized systems to avoid inventory stock-outs, transportation bottlenecks, and more.
  • Most operational problems can either be resolved quickly or avoided altogether with ERP software designed for distribution companies.
  • Today, more and more supply chain distribution and transportation companies looking for an advantage are investing wisely in ERP software.

Distribution management, supply chain and logistics planning can be few of the most challenging areas for any wholesale distribution company. If not properly monitored, common occurrences of events like rapidly increasing volumes of new information, varying timelines, and unplanned scheduling issues can become large challenges to overcome. This goes for unforeseen factors that can’t be planned for as well, like breakdowns, natural disasters, and unexpected disruptions to transportation channels. To minimize the impact of these scenarios and more, distribution companies can choose to leverage smart business management software platforms such as ERPs. These solutions designed specifically for distribution companies focus on simplifying operations and shortening the cash cycle with robust out-of-the-box and customizable solutions.

For years, distribution companies have been on the short end of the stick when it comes to implementing IT infrastructure capable enough to support their unique needs and requirements. While a quick search might indicate a majority of wholesale distribution companies operating on a similar model, a more in-depth investigation would highlight numerous differences and intricacies. An effective wholesale distribution ERP software can recognize specific requirements and provide solutions to address them based on the scale, geography, and operating model of a specific organization. This all points to ERP being essential for distribution channel management, boosting overall operational efficiency, and reducing costs.

Below are 5 more important reasons why the right ERP is a must-have for organizations looking to boost distribution and transportation networks

1.Increased agility With today’s market more dynamic than ever before, end-users are not only more aware of what they want but are able to access a growing number of options. This change in behavior requires manufacturers and wholesale distributors alike to rethink their approach. With the right ERP solution in place, both sales and distribution pipelines become much more dynamic, allowing distribution companies to communicate changes in requirements in real-time to simplify the order-to-shipment process.

2.Enhanced Data Management For any distribution company, managing inventory inflow and outflow is an enormous task, susceptible to repetition, recurrence, and multiple errors. This can be avoided by implementing a comprehensive ERP platform to automate data entry and facilitate high-end data and insight generation. The right ERP software in distribution offers significantly enhanced visibility and complete transparency for information being managed in a distribution network.

Figure: 1Why Do Distribution Companies Need ERP

Why Do Distribution Companies Need ERP

3.Efficient Inventory Management Properly managing today’s distribution operations includes actively monitoring supply chains, logistics, and inventory, which, when not managed effectively, can produce a significantly lower ROI. This is where ERP software for a distribution company can make a huge difference with things like built-in automation to track multiple items, real-time monitoring of goods to avoid stock-outs, and improved communication between stakeholders.

4.Streamlined Supply Chain Management To avoid disruptions in supply chains, companies need to take proactive measures to streamline operations and minimize the impacts of any global phenomenon that can potentially disrupt the supply network. An ERP software in a distribution company helps ensure a steady flow of goods, fortified communication amongst stakeholders, and complete visibility of the supply chain.

5.Improved Customer Relationships Today’s wholesale distributors are expected to anticipate their end user’s needs as market demands rapidly change. This helps organizations stay ahead of their competition, and able to respond quickly to their customer’s dynamic requirements. The strengthening of these customer relationships leads to an improved cash cycle, which further helps to avoid overstock. This leads to other, more conventional industries looking to improve customer retention with the right ERP.

Final Thoughts

Modern ERP software in distribution has evolved into complete end-to-end platforms designed to promote growth and improve both suppliers’ and distributors’ ability to do business under quickly changing conditions. Especially today, implementing the correct solution has become much more affordable, offering significantly improved response times, increased efficiency, and stronger customer relationships.

Key Takeaways

  • Choosing the right ERP for distribution is more crucial than ever in making your supply chain and distribution network highly dynamic, leaving your business in a much better position to respond to rapidly-changing market demands.
  • The main focus of ERP isn’t just operations management but also improving supply chain and strengthening customer relations.
  • Overall, sales and distribution cycles become much more profitable when the right ERP solution is in place.

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Why Pharmaceutical Manufacturers Should Choose Microsoft Dynamics

Why Pharmaceutical Manufacturers Should Choose Microsoft Dynamics 365 Finance and Supply Chain

Why Pharmaceutical Manufacturers Should Choose Microsoft Dynamics 365 Finance and Supply Chain 700 500 Xcelpros Team

Introduction

For businesses in the pharmaceutical industry, there’s a constant need to manage different challenges such as ever-changing regulations, severe production environment difficulties and complex equipment that can be difficult to maintain. Any equipment downtime could result in production losses and affect drug quality in the value chain, denting the brand image.

When it comes to pharmaceutical manufacturing, production schedules are incredibly demanding, especially when machinery is constantly under operation. These businesses work hard to ensure maximum availability of their assets in order to achieve production efficiency. This requires equipment to perform at full capacity with no downtime to create a competitive production environment.

Organizations in this industry looking to maximize their efficiency need to understand a few key points that help present a clear picture of the current state of plant equipment and manufacturing in general.

  • Poor equipment maintenance strategies can reduce a plant’s overall productive capacity by 5 to 20 percent.
  • Unplanned downtime is costing industrial manufacturers an estimated $50 billion each year.
  • Around three-quarters of all the plant equipment in manufacturing is more than 20 years old, which says a lot about the quantum of obsolete equipment and a significant cause of production downtime!.

Understanding equipment downtime, reliability and availability

For manufacturers in the pharmaceutical industry, having fully functional equipment is of utmost importance and means their business can operate normally. Understanding things like downtime, reliability and availability can be just as important if not more.

Scheduled Downtime is important for changeovers, cleaning, tool changes, early shutdowns, personal breaks, or any unplanned events that may occur, such as breakdowns or any repairs that can affect the core business. Equipment reliability is related to the health of equipment and how optimally it performs a task while considering attributes like quality and performance, and equipment availability is the actual time that a machine or system is available for production as a percent of total planned production time.

These are undoubtedly some of the biggest concerns for pharmaceutical manufacturers, but they’re not the only things that these businesses are required to deal with, such as

  • Increased downtime: This can lead to Supply chain disconnects, lower production, missed deadlines and increased penalties.
  • Spiking maintenance costs: This usually results in businesses reducing maintenance which can lead to complete failures, severely impacting revenue and operations.
  • Production dips: Usually caused by gaps in asset or equipment availability, this can halt production and affect the company’s revenue.
  • Equipment repair: Without a preventative maintenance plan, businesses are required to perform repairs as needed. This leads to uncertainty when it comes to the status of equipment and prolonged downtimes.
  • Equipment replacement: Upkeep is always cheaper than replacement. When equipment isn’t properly maintained replacement costs can easily end up exceeding the total costs of having a basic maintenance plan on board.
  • Drug quality of lower standards: Unreliable or under-maintained equipment can unknowingly produce lower quality products leading to fines, penalties and costly recalls.
  • Drug safety risks: As equipment ages it becomes easier for contamination to occur, which could lead to additional damages.
  • Loss of reputation: Missed deadlines, poor quality and unsafe products can have a severe impact on revenue and brand recognition.

Figure: 1Factors Leading to Poor Equipment Maintenance

Poor Equipment Maintenance In Pharma industry

A big reason this all matters stems from the U.S. Food and Drug Administration’s (FDA’s) decision to include equipment maintenance as one of the risk-based preventive measures in Current Good Manufacturing Practices (cGMP). With the USDA considering equipment maintenance as a key function of cGMP, it easily becomes one of the most critical factors for pharmaceutical manufacturers’ compliance and will be subject to even greater scrutiny.

Microsoft Dynamics 365 has been a game-changer for the pharmaceutical industry

More and more organizations are better able to control their machinery and minimize “time-to-insight” with Microsoft Dynamics 365 capabilities designed to help businesses gain total control of their data, offering integrated analytics and workflows. Microsoft dynamics for pharmaceutical companies lets businesses speed up the movement of goods, eliminate waste due to costly shelf-life expirations and returns, and improve production efficiency across their entire line. Microsoft Dynamics for pharmaceutical gives companies the ability to achieve the following:

1.Ensuring centralized Quality Control (QC) and regulatory support Organizations can use integrated quality controls and lot traceability to link raw materials through each operation of the production process. This helps accelerate and simplify compliance with regulatory agencies such as the U.S. Federal Drug Administration (FDA).

2.Managing better inventory more effectively Pull inventory in sequence, employing “best before” management, and enabling customer service to ship lots that arrive with the correct amount of shelf life remaining. Employ either first expiry/first-out (FEFO) or first-in/first-out (FIFO) calculations for inventory reservations, picking, reducing inventory and eliminating waste.

3.Conducting extensive audit trails Incorporate electronic signature functionality into existing business processes, providing complete visibility into batch production and audit trails.

4.Meeting GMP requirements Manage electronic quarantines, quarantine release by user and material type, printed material control/ obsolete components, lot control/ segregation, lot tracking, and drug and hazardous material reconciliation.

5.Improving production planning Accurately model the processing of costly ingredients to help minimize overruns and underruns. Shelf-life planning helps account for expiration dates during production and distribution.

6.Protecting recipes and formulas Dynamics 365 helps document various ingredients, storage requirements, manufacturing processes, pH values, particle size, and much more – all with the ability to review at any given moment. D365 lets you set security restrictions to ensure that only approved users are able to make changes, further protecting your critical assets.

Final Thoughts

As the pharmaceutical industry continues to evolve and grow, the need to understand and adopt intelligent technologies like Dynamics 365 becomes more and more apparent. Implementing solutions like Microsoft Dynamics 365 for pharmaceutical and other.

Pharmaceutical manufacturing ERP softwares is the best way for companies to maximize their asset availability and track machine reliability, letting them drive towards increased productivity, higher quality products and enhanced safety assurance.

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Importance of Robust ERP in Sustaining Manufacturing

Importance of Robust ERP in Sustainable Manufacturing

Importance of Robust ERP in Sustainable Manufacturing 700 500 Xcelpros Team

At a Glance

  • ERP has been critical to the manufacturing sector, from business strategies to meeting increased demand for specific products.
  • While the manufacturing industry has long been reliant on ERP systems for effective business operations, recent events have highlighted their importance.
  • Experts are looking at comprehensive ERP products that can help them meet rising demand and elevate their business platforms for success in the future.

If the manufacturing industry had to describe 2020 in one word, most might go with ‘unprecedented’. Things like disruptions to Supply Chains, wildly fluctuating changes in demand, and shortages of materials have led to a state of disarray for organizations of every size. These organizations are looking to maneuver efficiently through these challenges and meet changing demands while remaining in compliance. This means that manufacturers’ top management bodies weigh options to reshuffle their business processes and strategies to accommodate sudden changes.

Going forward, businesses will need to change their production plan from top to bottom as the demand for certain goods like automotive, non-essential goods, and construction materials have gone down. In contrast, things like chemicals, ventilators, sanitizers, hygiene products, PPE, and various pharmaceutical raw materials have dramatically increased. This shift in demand calls for realignment and systematic operational implementation of business processes with a fortified ERP system.

53%

of the manufacturing industry expect COVID-19 to impact operations.

Source: National Association of Manufacturing (NAM)

Shown below are some of the biggest concerns the manufacturing industry has at the height of the Covid-19 pandemic:

  • Disruption of supply chains due to travel restrictions
  • Low or no availability of raw material
  • Skeleton crews on the production floor owing to the fear of exposure to the virus
  • Loss of revenue due to stalled production all over the world
  • Realignment of the workforce to accommodate working from home
  • Rapid change in demand patterns for certain consumer goods
  • Downward or backward fiscal growth.

The future sustainability of organizations of all sizes in the manufacturing sector will depend on current investment in tools, software, and systems to streamline, realign, and effectively manage business and production operations. Sustainable manufacturing practices can surely help companies boost their profits.

Figure: 1Challenges Faced by The Manufacturing Industry Due to Covid-19

Challenges Faced by Manufacturing Industry Due to Covid-19 Pandemic

The resulting wake of Covid-19 has compelled decision-makers from businesses in the manufacturing sector to reevaluate their business processes and automation to deal with supply chain bottlenecks effectively. This is where the implementation of an effective ERP system comes into play.

Listed below are just a few key strategic ways that a comprehensive ERP system like Microsoft Dynamics 365 for Supply Chain and Finance can help fortify the end-to-end manufacturing life cycle for companies in this industry.

1.Addressing Bottlenecks in the Supply Chain ERP systems have proven essential to optimizing the supply chain and providing top-to-bottom visibility of production cycles to avoid situations like stock-outs, inventory glitches, and logistical issues. Enterprise Resource Planning tools have become highly critical to businesses as global supply chains are disrupted. ERP systems help mitigate damages by overhauling the demand-to-supply strategy and optimizing the supply chain accordingly. ERP systems are also highly crucial in collating and classifying production data for complete visibility to workers on the shop floor and beyond.

2.Boosting Automation to Compensate for Skeletal Workforce Thanks to restrictions still in place, many factories continue to operate at 50% workforce or even less to maintain social distancing to mitigate exposure risks. This means that more manual operations are becoming automated, requiring planning, changes in hardware and software, training, and proper deployment of automation protocols. This can all be managed with the help of a robust ERP system.

3.Managing Change in Demand Since the pandemic, there has been a swing in need for certain commodities, such as automobiles, sanitizers, hygiene products, and ventilators. These rapid changes in the market require an ERP system that helps streamline raw material purchases, billing cycles, payroll solutions, last-minute logistical changes, generating a bill of material, and much more.

Boosting Manufacturing with Microsoft Dynamics 365

Comprehensive platforms like Microsoft Dynamics 365 Finance or Supply Chain help Improve efficiency and productivity for businesses in the manufacturing industry. The systematic tools assist with planning, logistical management, change analysis, data collation, capacity requirement management, and responding to rapidly changing needs.

Figure: 2Boosting Manufacturing with Microsoft Dynamics 365 ERP System During Covid-19

Boosting Manufacturing with Microsoft Dynamics 365 ERP System during Covid-19

Key Takeaways

The numerous changes that developed since the onset of Covid-19 have created significant setbacks for any business in the manufacturing industry; Savvy organizations that can use the right ERP software while investing in intelligent solutions will be in the best position for growth when this is all over. Here are some final points to remember when you think of ERP in the manufacturing industry.

  • The top executives and decision-makers in the manufacturing sector need to invest in smart manufacturing ERP software solutions to combat the changing demand and supply patterns.
  • Analyzing global and local goods and commodities requirements will be essential for running a manufacturing plant.
  • Manufacturers need to rethink their supply chain and inventory management strategies and implement proven and systematic resource planning tools.

Book a consultation for all your manufacturing process needs.

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Making Pharmaceutical Supply Chains More Resilient

Making Pharmaceutical Supply Chains More Resilient

Making Pharmaceutical Supply Chains More Resilient 700 500 Xcelpros Team

At a Glance

Building a resilient supply chain framework for pharmaceutical companies requires:

  • Understanding where the company is now.
  • Creating new business relationships with alternate raw materials suppliers, transportation providers, and other essential third-party businesses.
  • Weighing the benefits of a robust and versatile pharmaceutical value chain versus the impact on working capital.

Introduction

Pandemics, natural disasters, cyber-attacks, political turmoil, and other actions are beyond a company’s control. Any one or combination of them can thoroughly disrupt a smoothly running supply chain.

Critical supply chain areas getting battered by these disruptions include reduced or non-existent access to:

  • Essential precursor chemicals and components
  • Production facilities
  • Vital workers and managers
  • Transportation resources to bring in raw materials and ship out finished products

The unquestionable first requirement to improving supply chain resiliency is having access to accurate data and knowing what to do with the data-driven insights. Data sources such as the Industrial Internet of Things (IIoT) provide real-time information, and applications such as Microsoft Dynamics Supply Chain Management helps users evaluate existing information.

Precursor Chemical Supplies

A 2020 report from Avalere states that U.S. biotech firms making medicines here get their active pharmaceutical ingredients (APIs) from U.S. suppliers – import them or import finished products. These precursor chemicals accounted for $86.5 billion in the U.S. alone during 2019.

One issue U.S. companies are facing is the location of active pharmaceutical ingredient (API) manufacturers. According to the U.S. Food and Drug Administration (FDA), the top four places are:

  1. 1.U.S. – 28% (510 facilities for FDA regulated drugs)
  2. 2.European Union – 26%
  3. 3.India – 18%
  4. 4.China – 13% (230 facilities for FDA regulated drugs)

Figure: Percentage of API Sources in U.S. Dollars

Percentage of API Sources in U.S. Dollars

Figure: API manufacturing facility locations

API manufacturing facility locations

Canada and the rest of the world produce the remaining 20 percent of APIs used in medicines. Also, the FDA report states India, the EU, and the rest of the world have 1048 facilities making FDA-regulated drugs.

Adding to the importance of having resilience in the pharmaceutical supply chain are potential supply chain disruptions caused by using overseas suppliers. These include recalls, such as two from China cited by the FDA within the last six years.

One way to counter a dependency on foreign API supplies is by using advanced technology to produce chemicals and medicines at lower costs, the FDA suggests. Using the continuous manufacturing (CM) process to make finished products instead of producing batches with gaps between steps can be more effective.

Another method of reducing reliance on foreign API suppliers is using advanced technology. Newer methods producing APIs and finished dosage forms (FDF) helps in supply chain management in the pharmaceutical industry. The ability to rapidly respond to changes in demand, using smaller physical footprints that require smaller facilities, helps reduce pharmaceutical manufacturing costs potentially, offsetting overseas production advantages. High tech production methods, such as those in smart factories, also tend to have lower environmental impacts.

Pharmaceutical companies considering boosting their pharmaceutical value chain using this method can get help from the FDA. The FDA has an Emerging Technology Program (ETP) described in “Advancement of Emerging Technology Applications for Pharmaceutical Innovation and Modernization Guidance for Industry.”

The FDA is also working on a framework to develop miniature mobile manufacturing “Pharmacy on Demand” platforms to produce essential drugs at or near the point of care. This method, while requiring capital costs, provides the means of eliminating delivery costs.

Risk Sources

Before making changes to the current supply chain, CFOs should look at four primary sources of risk:

  • Sourcing of APIs and other raw materials risks. Counter risks by locating secondary suppliers and establishing working relationships with them.
  • Staffing and transportation risks. Consider having access to remote workers plus multiple methods of delivering finished products to customers.
  • Inventory risks. Contrast cash flow needs with inventories to be able to withstand short-term disruptions while also accounting for perishability.
  • Distribution risks. Be able to use multiple methods to deliver finished products to customers. Consider outsourcing part of the distribution to withstand problems in that area.

Strategic Questions

Before investing in building a resilient supply chain, CFOs would want to know:

  • How can we obtain the most accurate data on what we currently have? Is investment in IIoT sensors and other technology warranted?
  • What are our priorities based on what we have learned from the current pandemic? Is digitizing our data stream the top priority, or is securing a second or third API source more critical?
  • How do we balance internal conflicts? What will we do if a secondary API source that can deliver in the event of a natural disaster is more expensive than our primary source that cannot provide when we need the raw materials?
  • How do our risks integrate with risks from our third-party partners? How will a disaster impact their ability to supply critical products or services we need?
  • What do we consider a resilient supply chain? How much impact on near-term profitability is acceptable if we ensure that we can continue operations in the event of a significant supply chain disruption?

By the Numbers

$16 trillion (i.e., $16,000,000,000,000): Estimated total cost of the Covid-19 pandemic in the U.S. alone.

$85 billion (i.e., $85,000,000,000) lost by the Nasdaq Biotech Index in the week ending March 6, 2021, its third weekly loss in a row.

$242 million (i.e., $242,000,000) lost by the Health Care Select Sector SPDR Fund (XLV) in the week ending March 6, 2021, bringing the total loss to date to $1.68 billion

Source: U.S. National Library of Medicine and National Institute of Health

Strategies for Greater Supply Chain Resilience

Figure: 1A roadmap to digital transformation to a resilient supply chain

A roadmap to digital transformation to a resilient supply chain

According to a recent Deloitte article, CFOs can reduce their chain disruptions and improve their supply chain resilience by using these strategies:

  1. 1. Identifying and mitigating their most significant supply chain weaknesses. Questions to consider include: Where are your API manufacturers located? Are there alternative sources able to deliver the required quantities when needed? Are the raw material sources within an acceptable range of the production plants? Identifying these alternative suppliers helps ensure a more continuous input of raw materials.
  2. 2. Prioritizing investments in the supply chain infrastructure to ensure significant delays do not occur when disaster strikes. Technological improvements supporting product storage and movement (e.g., Microsoft Dynamics Supply Chain Management) can make processes more transparent and improve efficiency in financial transactions and information exchanges.
  3. 3. Balancing the supply chain investments with competing company requirements, such as costs and services. Deloitte cites, “managing working capital while restarting operations and rebuilding inventory as one major challenge of a supply chain disruption.”
  4. 4. Creating a playbook to handle the causes of supply chain disruptions.
  5. 5. Implementing the updates from the standpoint of cost, speed, and efficient operation. The Deloitte report states that supply chain leaders should work with CFOs to determine the effects of supply chain changes on their working capital.

Before Making Any Decisions

Before making changes to their current supply chain, CFOs, chief technology officers, and other executives should consider:

  • Evaluating where the current pharmaceutical supply chain stands.
  • Creating a plan or series of methods for sourcing alternate raw materials, workers, and production facilities should any natural or human-made disasters strike.
  • Analyzing the cost versus benefits of making the current pharmaceutical value chain more robust and resilient.

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Three actions CEOs can take to get value from cloud computing

Three actions to take to see cloud computing benefits

Three actions to take to see cloud computing benefits 700 500 Xcelpros Team

Cloud computing benefits: At a glance

  • The decisive role of C-suite executives in a company’s digital transformation is crucial in driving business towards success.
  • When it comes to the goals and benefits of cloud computing, CEO’s need to take charge and be involved in strategy to make sure that the blueprint matches the company’s requirements.
  • CEOs need to align with the CTOs and CIOs to get maximum advantages of cloud computing and be sure that their digital transformation journey is a smooth one.
  • Partnering with a business advisor can make or break a digital transformation.

Introduction to the benefits of cloud computing

The last decade has seen accelerated growth and transformation in various industries as they embrace the digital thread. There has been a pressing need for companies to streamline processes and optimize operations to go agile. Then, the Covid-19 pandemic left a mark on every industry, making agility (and flexibility) an inevitable aspect of business growth. Remote work is the new normal, so the advantages of cloud hosting are even more apparent.

There are quite a few benefits and moves a company can make around their move to cloud computing. These strategic moves must start at the top and cascade down for maximum efficiency. This is where CEOs come into the picture as the catalysts of accelerated growth. You can take your company down the path of agility and explore the benefits of cloud computing. When these actions are taken while closely with other C-level executives, such as your CTO and/or CIO, the more likely you are to be successful in your transformation.

 

32%

of IT budgets will be dedicated to the cloud within the next 12 months.

Source: Bloomberg

Any number larger than 30% of a budget is a significant amount. When a company makes such a big investment, there is a lot riding on the shoulders of the person in charge. Any CEO guiding their company through digital transformation can harness economic advantages of the cloud. Taking decisive actions while collaborating with other C-level execs can aid in the process. Read on to learn more.

Three game-changing actions CEO’s can take when it comes to cloud adoption

It is important to understand why the role of a CEO in cloud strategy is so important. To make cloud adoption a success for your company, a CEO needs to strategize transitional moves and make sure that all cogs in the machine are functioning properly for a smooth journey.

According to David Cearley, Vice President and Gartner Fellow, “Organizations that do not have a high-level cloud strategy driven by their business strategy will significantly increase their risk of failure and wasted investment” (from “Cloud Strategy Leadership” by Gartner).

Following these steps can help to ensure employees understand the importance of cloud computing and are comfortable with the change so that the company can see all the benefits from your digital transformation.

1. Communicate change within the organization, to the organization.

First of all, as a company executive, this might be one of the most important actions you can take to ensure a successful cloud implementation. As you know, any disruptive change within an organization creates certain resistance amongst employees. While some might be worried about their skills becoming obsolete, others may feel apprehensive about the security of cloud-based systems.

Basically, with direct communication, employees stay in the know-how and won’t be taken back by any steps in the process which may change their daily routine. This can occur through in-house campaigns, alignment with department heads, announcing new HR policies, and many other means of organizational communication- all helping to ensure a smooth cloud implementation.

2. Keep the financial flow stable.

Second, meeting the goals and benefits of cloud computing can only happen through proper funding. As a CEO, creating a financial funnel that supports every step in the company’s cloud transition journey is vital. Seeing  the advantages of cloud computing may take some time for your business. Because of this, being sure that the financial backing is stable and consistent is very important.

Figure 1: Benefits of Cloud Computing

Cloud Adoption Strategy Drivers

 

3. Create a cloud business strategy blueprint.

Third, transforming a businesses processes is only as efficient as the planning that goes into the transformation. Creating a strategy and supporting technology operating model to get optimal value from the move to cloud computing is crucial. Such a model harmonizes interactions between IT and business processes.

4. Partner with a business consultant to aid in strategy and execution.

Finally, there are companies whose sole mission is to aid other businesses in moving to cloud computing. Because this is the sole focus of these businesses, their expertise can be the one thing to make an implementation successful. Consider partnering with a business advisor or consultant to assist with planning, strategy, and change management during your move to cloud computing.

In summation, reaping the advantages of cloud computing can happen via high-level strategy. Seamless harmonizing amongst CEOs, CIOs, and CTOs can turn a digital transformation journey into a profitable benefit for the business.

Cloud computing benefits: Key takeaways

  • CEOs should be looking at cloud computing strategies from a long-term point of view and ensure that the company is allocated with the budget and resources for cloud implementation.
  • Proper communication is the key in migrating to the cloud: employees should receive communication from C-suite executives or department heads to develop trust.
  • Partner with a business consultant who has done this before and can provide expertise in planning and moving to the cloud.
  • Simply moving to the cloud won’t generate value for a business. Higher C-level executives should take lead in their company’s digital transformation to make sure the investment makes its return.

Take your first step towards moving to the cloud with a consultation from XcelPros.

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Challenges of pharmaceutical supply chain banner

Top 8 Challenges of Pharmaceutical Supply Chain

Top 8 Challenges of Pharmaceutical Supply Chain 700 500 Xcelpros Team

At a Glance

  • The Covid-19 pandemic not only came as a health threat, but it also disrupted the world’s socio-economic thread. Industries like pharmaceutical and biotechnology were at the forefront attempting to find solutions.
  • Pharmaceutical industry supply chain challenges that concerned top executives include shortage of raw materials, unprecedented changes in demand pattern, inability to plan lead-times and shortage of labor.
  • The pharmaceutical industry’s supply chain efficiency still has room for improvement and may need some transformative changes to thrive in the new normal.

Pharmaceutical supply chain challenges have been a major cause of concern for the industry throughout 2020. The challenges are still very much prevalent, even as the world moves ahead in the era of the new normal. This pandemic caused a major global socio-economic impact and led to disruption in almost all facets of the industry. Modern companies equipped with the right tools and technologies have been quick to adjust to the changes. Organizations that still functioned on archaic systems were struggling to adapt to the business processes changes brought about by the pandemic. Slow to adapt companies had to put in more effort to understand the needed changes and adapting to the changes without the right technologies in place was daunting.

Figure: 1Major Pharmaceutical Supply Chain Disruptors

Cotributors of  Pharmaceutical Supply Chain Challenges

Added to that was the inability of companies to quickly onboard onto newer applications and get into the rhythm of modern cloud-based solutions. Some of the major issues that surfaced during the pandemic are:

  1. a.The demand for therapeutics and/ or vaccines led to an overdrive of pressure on the industry.
  2. b.The lack of resources and slow global travel have increased pharmaceutical supply chain disruptions.
  3. c.Changes in quality standards have added new tasks to the workforce that were not part of their day-in-the-life and had to adapt to rapidly.
  4. d.Changes in quality testing created adjustments in the test specification and additional steps in testing.
  5. e.Disintegrated systems made it harder for the workforce to stay agile and adjust to the changes that came their way.
  6. f.Inability to manage supply-demand cycles.

70%

of the leaders said that the pharmaceutical supply chain was vulnerable to ongoing problems caused by the continuation of the pandemic and that on-time, in-full delivery of medicines had deteriorated by almost 50 percent within the first few months of the pandemic.

Source: IDC Whitepaper Report

While modern manufacturing companies did rise to the challenges and leveraged solutions such as cloud applications, automation, Artificial Intelligence (AI), Machine Learning, and Big Data to their advantages, many risk-averse pharmaceutical companies are still prone to supply chain challenges due to the lack of right tools in place to make them nimble. Let us look at the top 8 concerns of the pharmaceutical industry supply chain that still are pressing concerns:

1.Unprepared for further disruptions: Different countries worldwide are struggling with second or third waves of the pandemic (and many have reported new mutant strains of the virus). These continuous disruptions have led to major disturbance in the pharmaceutical distribution system.

2.Technological bottlenecks are prevalent: The pharmaceutical industry has been highly apprehensive and traditional in adopting newer technologies. While the last decade has seen major leaps, there are still many bottlenecks in leveraging technologies to their full potential.

3.Shortage of raw material: The inability to plan effectively during the pandemic can cause many hurdles if procuring raw materials. Knowing lead times and accurate inventory quantities without a planning tool can slow you down significantly as you try to extrapolate data and understand your supply schedule.

4.Standard operating procedures and processes: As workforce within the pharmaceutical industry needs to be onsite, proper SOPs need to be set. This would add new processes that warehouse personnel need to be trained on. A lack of the right kind of training tools can add to the burden.

5.Managing cold storage facilities is resource-intensive: Some of the products have to be stored at very low temperatures to ensure that the potency and formulation remain intact. This would need pharmaceutical supply chains equipped with refillable dry ice containers or specialized freezers, both of which are not budget-friendly options.

6.Pharmaceutical safety guidelines and regulations differ across Borders: The pharmaceutical industry has to be very tenacious and alert when adhering to the safety guidelines and regulations. However, pharmaceutical supply chain challenges get magnified as the raw materials and drugs cross borders and these regulations keep on changing.

7.Rapid drug delivery: The historical task of bringing medicines to market is a race against time. Pharmaceutical operations and supply chain management handling need to be as efficient as they come to ensure lesser bottlenecks and plausible errors in these testing times.

8.Lack of integration across processes: When your inventory, manufacturing, labeling operations don’t talk to each other and are manually managed, the error rate will go up and business productivity will go down.

The year 2021 will probably push the pharmaceutical supply chain to its maximum limit yet. However, with the right strategy, technologies, and solutions, the pharmaceutical sector can rise up in these challenging times.

Key Takeaways

  • Pharmaceutical manufacturing and distribution companies are facing a once-in-a-lifetime level of challenge and they need to streamline their operations to ensure the efficiency of supply chains.
  • The pharmaceutical supply chain challenges have been a part of this sector for a long time and companies that are not properly equipped will tend to struggle more than others. This is the right time to transform to be equipped with the right technologies for a better tomorrow.

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Enhancing Chemical Plant Operations to Make it Smart Factory Ready

Enhancing Chemical Plant Operations to Make it Smart Factory Ready

Enhancing Chemical Plant Operations to Make it Smart Factory Ready 700 500 Xcelpros Team

Introduction

Creating an Industry 4.0 smart factory requires time, planning, money and employee buy-in. Companies are advised to develop a roadmap showing what they want to do before they start. Improving communication through a digital platform ensures alignment between people, processes, and technology.

Smart factories are facilities using computer technology to transmit real-time status of every machine to a central hub. The data is used to make decisions on the spot, avoid production delays, and provide opportunities to improve efficiency.

In these factories, a combination of electronic sensors connected to a computer network provides a constant flow of information. When combined with artificial intelligence software, the computers make autonomous decisions, improving chemical plant production.

In the United States alone, 86 percent of manufacturers believe that smart factories will be the main driver of competition by 2025.Source: Deloitte

How it Works

Enhanced communication between machines means: Receiving tells Procurement what raw materials arrived and when. Procurement knows what supplies are on-hand and what must be ordered. Machine A has the materials it needs to create products. Machine B is working on a different product instead of being idle while waiting on Machine A. Machines A through Z are programmed to perform their jobs and let human workers know when potential problems may occur. Sales knows what finished products are available for shipping and what is in the pipeline. Customers know when they can expect deliveries in the time and quantities they require. Best of all, this information is available in real-time, so everyone knows potential problems and how they can work around them.

Acquiring data from the industrial internet of things (IIoT)-enabled devices and rapidly analyzing it turns standard factories into smart chemical plants.

These plants can rapidly view their entire supply chain from inventory to production to sales. Having the ability to keep track of production flow and ensure the supply chain flows smoothly is the function of specialized software such as Microsoft Dynamics Supply Chain Management.

Converting an existing plant using older manual devices, though, takes time, effort and money. Thought and a lot of planning are required to bring an analog factory up to this level gradually.

Critical smart technologies include hardware components such as sensors, industrial internet of things (IIoT) connections, factory floor networking connections and cabling plus data storage for millions—possibly billions—of datasets. Company computers—either on-premises or connected via the cloud—require software able to organize and manage the data using artificial intelligence. One such product is Microsoft Dynamics Supply Chain Management.

Figure: 1 Working of a Connected Factory

Connected Chemical Factory

Industry 4.0

As part of the Fourth Industrial Revolution, commonly known as Industry 4.0, smart factories build on computerization added to manufacturing processes in the mid 20th Century’s Third Industrial Revolution.

Above and beyond automating individual machines, Industry 4.0 smart chemical plants have:

  • Dramatically increased data collection, allowing more accurate decision-making.
  • Increased automation to encompass entire production runs. This produces goods more efficiently, including during times when humans are not present.
  • Improved flexibility allowing factories to mass-produce lots in any size from one unit on up.

5% Percentage of factories are fully “smart”.

30% Percentage of factories are being updated to smart status.

65% Percentage of factories are not making progress toward smart status.

Source: Deloitte Insights

Smart Factory Challenges

Factory owners face several potential barriers to converting an existing facility into a smart factory running more efficiently with minimal downtime and defects. These barriers may include:

  • Employees accepting ongoing training and developing needed skills. Deloitte estimates a 2 million worker shortage in the US alone over the next decade.
  • The cost of updating factory floor machines to include sensors and information sharing capabilities. Some existing machines can be modified, while others may require replacement.
  • Networking all data collection points to ensure a smooth, continuous information flow. The information can flow to a central server on the premises or remotely.
  • Accepting the concept that smart factories cover the entire company, not just the production floor.
  • Ensuring all updated devices are compatible and can be integrated into a complete network.

Leading the Conversion Change

Some companies appoint “change champions” to lead their company into the smart factory 4.0 era. These people are often tasked with making the technology updates relevant to workers.

Change champions, which Deloitte’s research suggests, should be from the top-down (e.g., upper managers) and bottom-up (e.g., factory workers), help gain employee buy-in.

Their chief focus is answering the question, “What’s in it for me?” from individual workers’ perspectives. For example, change champions explain how mastering automation gives workers the ability to head off potential problems before they occur. Fewer problems in the production process mean greater output—and likely more sales—which benefits the entire company.

Change champions also explain to staff how they will benefit by gaining the new skills smart factories require. Additional training equals more skills and that translates to more opportunities for improved pay and job security.

Chemical Plant Automation Devices

One step existing factories must take to become smart chemical plants is updating equipment. For example, valves that factory workers open and close manually should be replaced by semi-conductor enhanced valves that do it automatically.

Among the many chemical treating instruments required to provide a smart factory technology with the information it needs are:

  • Smart pressure transmitters equipped with microprocessors and semiconductor pressure sensors that can directly measure pressure in pipes.
  • Microprocessor-equipped differential pressure transmitters to measure flow rates, pressure and liquid levels of gases, fluids and steam.
  • Flowmeters for measuring gas, steam and liquid, including vortex models that permit correcting temperature and pressure.
  • Level transmitters equipped with microprocessor sensors for measuring levels in liquids.
  • Control valves such as eccentric three-way rotary valves for mixing or dividing fluids.
  • Temperature controllers to ensure temperatures are within a device’s operating range and notify personnel of potential equipment problems before they occur.

The combination of electromechanical devices such as these with monitoring software lets workers watch conditions on the smart factory floor from literally anywhere: an office in the plant or a laptop on the beach.

Computerized positioners lets trained workers know the deviation between a set valve opening and the actual valve opening. This knowledge helps workers detect signs of impending valve failure before it occurs.

Creating A Roadmap to Success

Companies wanting to update their factory to a smart chemical plant may want to follow a path similar to this one:

  1. 1.Map a smart manufacturing strategy based on each firm’s specific industry dynamics. Be agile and able to change direction when real values begin emerging.
  2. 2.Create a smart pilot project with proofs of concept that demonstrate the project’s value to the company. Embrace failure and learn from mistakes.
  3. 3.Define the required capabilities using a scalable data model. Ensure the technology used in one area communicates with that used elsewhere.
  4. 4.Identify smart manufacturing insights appropriate to the company, such as cross-functional data analytic teams. Share information between teams to avoid duplicating efforts while gaining additional insights.
  5. 5.Institutionalize new approaches to prevent older, less efficient methods from creeping back into the updated operations. Show the staff concrete examples of how the technology upgrades are making a proven difference in the chemical plant operations.

Figure: 2 Creating a Roadmap to Success

Roadmap to Success

Key Takeaways

  • Converting an existing factory to a smart chemical plant requires time, effort, money and patience. Factory owners and managers must overcome barriers on the way to achieving their goals.
  • One of the most important tasks is appointing Change Champions at the top (executive) and bottom (factory worker) levels who work together to get the entire workforce on board.
  • Advancing into the Industry 4.0 era means updating devices to provide a constant flow of data. Companies should create a roadmap showing how they will move from their current position to be a smart factory.

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Reducing the Risk of Pharmaceutical Non-Compliance with Technology

How Technology Can Reduce the Risk of Pharmaceutical Non-compliance

How Technology Can Reduce the Risk of Pharmaceutical Non-compliance 700 500 Xcelpros Team

At a Glance

  • Pharmaceutical manufacturing companies are investing more money and resources to assure adherence to regulatory compliance.
  • Non-compliances need to be managed and tracked through their lifecycle, and using a digital platform eases the end-to-end process and follows it to completion.
  • The first step towards regulatory adherence is to thoroughly understand the compliance requirements and form a dedicated process to comply.

Many pharmaceutical companies have restructured their financial and resource allocation models to invest more in adhering to compliance. Compliance requirements around the globe have grown in past decades. Each country has differences in safety standards, and global companies have to ensure they meet local requirements. Companies need better management and tracking of non-compliance. This article discusses the ways to reduce risks of non-compliance in the pharmaceutical industry. Manufacturers and distributors have dealt with compliance issues in the pharmaceutical industry. Companies have to conform to multiple complex and varying regulatory norms and safety standards. All the stages involve detailed compliance requirements, from procuring raw material to producing finished goods and quality testing of the final product. These complexities have further multiplied in recent years because of:

  • Addition of several more regulations globally in the pharmaceutical and life sciences sector.
  • Differences in the rules and regulations related to pharmaceutical compliance across different geographical regions.
  • Absence of a viable infrastructure to manage and track non-compliance.
  • Unclear SOPs and redundant record maintenance practices often lead to pharmaceutical manufacturing non-compliance.

Apart from these, non-compliance can result from other various smaller factors like faulty equipment, maintenance issues, faulty formula controls/ lab controls, etc. All contribute to quality compliance in the pharmaceutical industry. This is the reason that pharmaceutical and life sciences companies spend a fortune to avoid non-compliance. The costs of non-conformity are very high and thus, companies want to make sure that they adhere to the rules and regulations.

40%

of the pharmaceutical IT budget is spent on regulatory compliance.

Source: Gartner

Figure: 1 Major Factors Affecting Compliance in Pharma

 Major Factors Affecting Compliance in Pharma

So how can pharma companies leverage technology to mitigate the consequences of non-compliance? Here are some ways that experts believe newer tools and innovations can help in better pharmaceutical compliance management:

1.Making use of the right tools: Documentation and record maintenance are a big part of the pharmaceutical industry’s compliance processes. Conventionally these documents have been manually maintained, which can lead to both errors and oversights. However, newer pharmaceutical software platforms come with the ability to gather and store data efficiently. It is essential to track user behavior and user audits to ensure compliance. A compliance management system with audit tracking and reporting tools can avoid non-compliance and improve overall product quality.

2.Leveraging integrated labeling: Pharmaceutical companies struggle to manage compliance as they enter newer territories and markets. There are different labeling practices and regulations which are challenging to manage. The labeling practices keep going through changes and updates even in familiar territories, making it essential for pharmaceutical companies to stay on top of these changes. To tackle labeling issues, companies can leverage the automated labeling platforms wherein the data can be auto defaulted from the different processes such as receiving, production and shipments. Inbuilt label printing within business process workflows avoids user errors and enforces process compliance. With integrated labeling within the ERP, users are equipped to manage changes and make the labeling process run smoothly.

3.Standardizing processes across the organization with a common technology platform: Major pharmaceutical manufacturers and distributors are tying up with technologists to deploy a common technology platform and implement it across their locations. Companies that invest in business process uniformity will witness business improvement and growth. Quality issues often arise due to non-compliance of processes, undefined procedures, changing equipment and labels, etc. Many companies find that quality is impaired when processes vary from location to location. With the latest technology platforms, organizations can centrally assure that standardized practices are being followed across all locations.

4.Effective strategies to managing data: Non-compliance in the pharmaceutical industry is often a result of a poorly managed information loop. Systems supporting pharmaceutical manufacturing and distribution generate enormous data. When data is managed systematically, the right information is made available to appropriate users. The right system can notify regulatory changes, changes in formulations, or process variations. Every data point serves as a crucial piece of information that can guide users to be more proactive in conforming to business processes. Data management and analytics platforms are equipped to enable pharmaceutical companies to report anomalies as they occur. Dynamic reporting cumulatively helps in better quality compliance.

The Covid-19 pandemic has added impetus on pharmaceutical companies to adhere to regulations while working on therapeutics and vaccines at an unprecedented speed. Companies that leveraged the latest machine learning, analytics, and other IoT tools/ platforms, perform better.

Pharmaceutical companies are always looking for newer methods to balance quality compliance and productivity.

Johnson & Johnson, for instance, has a comprehensive quality management framework in place for continued focus on compliance and quality, amongst other essential parameters. The latest technologies and innovations back this framework.

All in all, reducing the risks pertaining to compliance issues in the pharmaceutical industry requires a well-planned and executed technological strategy. With the latest innovative platforms, companies can ensure adherence to quality compliance regulations in the industry.

Key Takeaways

  • ERP, automation, data analytics, and machine learning are imperative in enabling pharma companies to mitigate the risks of non-compliance.
  • To reduce the consequences of non-compliance, pharmaceutical companies need to strategize their technological moves.

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References: Reducing the Risk of Noncompliance

How do smart factories help boost your supply chain

How do smart factories help boost your supply chain?

How do smart factories help boost your supply chain? 700 500 Xcelpros Team

At a Glance

  • Smart factories can use technology to boost productivity and increase quality. Merging data and insights from the shop floor with the supply chain and the entire organization can uncover ways to improve operational efficiency and boost business relationships.
  • By connecting devices and sharing information, smart connected factories permit automatic optimization. The machines can adapt to changing conditions in real-time and run the entire production process without human intervention, a white paper from Deloitte states.
  • A smart factory is one where information is continuously shared between devices and resources. Sharing this information reduces waste, thereby increasing efficiency and productivity.
  • It impacts the supply chain by anticipating needs and automatically ordering materials. That in turn keeps the factory running at maximum efficiency.

The smart factory represents a leap forward from more traditional automation to a fully connected and flexible system.Source: Deloitte

Traditional factories tend to have discrete machines and production lines. Information gathered from one device stays with that device until manually uploaded into a computer network.

Smart factories eliminate the barriers between machines, using computer sensors to monitor every stage and every process, producing huge volumes of data. The information is shared vertically on the factory floor and horizontally with other departments. This method lets the company rapidly adapt to marketplace changes, expanding its offerings and encouraging innovation based on customer needs. Smart connected factories are much more than just machines knowing when to open and close valves. They integrate the entire operation—including supply chain, manufacturing, information technology (IT) and operations technology (OT)—into one unified, agile organization.

Characteristics of a smart factory

Smart factories share five characteristics. They are:

  • Connected across machines and departments
  • Optimized for reliability and predictability
  • Transparent for quick decision making and order tracking
  • Proactive for identifying potential problems before they occur and restocking materials before running out
  • Agile for quick changeovers and product modifications

Benefits of a smart factory

Important benefits of a smart factory include:

  • Using data to create pattern identification and mapping the production process. This method gains production insights and allocates resources more efficiently.
  • Identifying and logging all process problems from machine and worker input.
  • Identifying waste creation points and processes.
  • Sharing data not only with the factory floor but with sales, marketing, finance and other departments to improve overall results.
  • Mastering the smart supply chain, permitting advance ordering of critical components before running out of them and delaying production.
  • Customizing small orders, permitting small batch creation when machines are not in use on large projects.
  • Diagram an ideal state.
  • Develop a plan to make the ideal state a reality.
  • Monitor and continually adjust new processes—including educating and training employees—ensuring maximum efficiency.

How it Works

The information process begins by using machine sensors and operators to capture data points during the 7 Flows starting with the supply chain in the form of raw materials. Each of these flows is part of the Lean Manufacturing Process.

Seven Flows

The seven flows involve:

  1. 1.Raw materials
  2. 2.Work in progress
  3. 3.Finished goods
  4. 4.Operators
  5. 5.Machines
  6. 6.Information
  7. 7.Engineering

All of the flows working together tend to efficiently produce products with few defects, Kettering’s article states.

Software such as Microsoft Dynamics 365 Supply Chain Management is designed with these concepts in mind.

For example, Microsoft Dynamics 365 Supply Chain Management allows factories to integrate industrial internet of things (IIoT) and artificial intelligence in the process flows.

Technical Advances Enabling Smart Connected Factories

Recent technical advances permitting the creation of smart factories include the development of:

  • Sensors collecting information, providing access to various activities and processes.
  • Using connected IIoT (Industrial Internet of Things) devices transmitting the sensor data to a database that in turn, massages the data to identify and correct inefficiencies.
  • Analyzing data as it is being collected. This permits rapid responses to changing situations, such as correcting a manufacturing defect as it occurs.
  • Employing AI (artificial intelligence) coupled with machine learning permits self-correcting when detecting errors such as closing an open door that might affect a temperature-sensitive section.
  • Relocating some IT resources to “the cloud.” Cloud Computing reduces data costs by transmitting it to a remote location where an interconnected network of computer servers processes, shares and stores data in a secure location away from the factory.
  • Running a digital version of a process in advance. By identifying and correcting potential errors and sticking points in advance, actual production is not affected.
  • Keeping data secure from outside cyber threats and attacks such as ransomware or hacks that steal data or damage or destroy critical components.

When many people think of the Internet of Things (IoT), they visualize home products such as lights that turn on and off when people enter rooms, saving electricity. Maybe they consider newer smart refrigerators that let homeowners use an app on the attached touchscreen monitor to order food items when they are running low.

The IIoT expands this connectivity from computers and the home to computers and industrial machinery. For example, it allows remote workers to monitor temperatures and automated chemical blending, ensuring the correct mixtures.

Figure: 1Functions coming together within smart factory

Functions coming together within smart factory

Why Update Now to a Smart Factory Solution?

The rapid pace of technological innovations means that the cost of making some of these updates—computing speeds and data storage, for example—has dropped. Technology is more sophisticated allowing systems not only to gather information but interpret it and automatically make adjustments.

A more complex supply chain means manufacturers must be more nimble than ever before while also adapting to constantly shifting priorities.

Merging parts of IT with parts of OT, in combination with device hardware and software such as Microsoft Dynamics 365 Supply Chain Management lets factories analyze their data now in real time for smart supply chain management.

Smart Factory Categories

Smart factories come in four categories, all based on data.

  1. 1.Available—but not accessible—data that must be organized before being transmitted.
  2. 2.Accessible data, which is organized and stored in ways that permit analysis.
  3. 3.Active data, which can be analyzed by computer software such as Microsoft Supply Chain Dynamics 365.
  4. 4.Machine-controlled modifications using solutions identified earlier, all with limited human input.

Making Factories Smart

Owners and managers may want to start with a single device, get it working the way they wish and then gradually expanding to a full production line. Companies considering updating an existing factory will need to have methods of obtaining data from the factory floor, which might require updating or replacing some machines. The cloud can help with processing and storing the information but data collection takes place locally.

Investments in other technologies—including AI, augmented reality and optical sensors—may be required to understand the data and digitize the production process.

Another important change is staffing. Even though much of the work will be automated, skilled workers are still required. This could involve realigning departments and eliminating or drastically changing individual roles.

Key Takeaways

  • Technological changes are turning the dream of smart factories into reality.
  • Smart Factories have the ability to highly automate many repetitive steps using a combination of device sensors and computer software.
  • Factory data can be used to create artificial production lines. Running them virtually lets managers spot potential problems before affecting actual production.

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